Tag Archives: plasma cell content

Everything’s coming up roses

Yesterday’s knitting and crochet should have ended up looking like the rose tea cosy I made last year. And it did last night but not so much after I inadvertently put it in the washing machine this morning on a synthetics cycle. ‘I’ll just bob it in with the baby jacket and crochet blanket’ I thought and in my haste I neglected to register that it was wool. What was odd though was that the roses, which were pure wool, didn’t felt as much as the cosy body. I don’t know whether the fact that they were crocheted had anything to do with this or not.

I should have included something to show the scale but needless to say a very small teapot now would be required.  As it was to be a late Christmas present I’ll need to redo it. I initially thought about cutting the roses off and knitting another base but couldn’t find the right colour as I’d used the last of the green. So I ended up deciding on a whole new colour scheme.

I claimed my bed at the Royal this afternoon (or yesterday afternoon as it is now since dialysis was a bit delayed meaning I’ve only just been hooked up to the two bags of chemotherapy goodies) after B had cooked us a nice lunch. He’d asked me on Tuesday to ask about the results of the bone marrow biopsy but I’d forgotten plus as I said to him I didn’t know if the dialysis unit would have been able to access them or indeed interpret them if the findings weren’t straight forward. When we saw one of the junior doctors earlier B reminded me that I hadn’t asked so I said I would when she came back. I forgot again but not to be put off B asked instead. She said that she couldn’t let us know but she would get one of the registrars to go through them with us.

Later one of the registers popped in and went through the treatment plan and then got to the results of the biopsy. As we knew the aspirate sample wasn’t any use and it turned out that the trephine was smaller than the ideal length of 2cm but results had been obtained from this.

Now bearing in mind that the sample could have been taken from a low plasma point in the bone marrow, but which had been 90% in November, and it could be higher in other places there was nothing! Yes, NOTHING. Well he did say it would be classed as 1% and I believe, if memory serves me right, that for myeloma to be diagnosed from a bone marrow biopsy it needs to be above 6%. I’ll be getting another one after this cycle of DT-PACE to confirm the results but basically if it was this level somewhere it wasn’t going to be as high as 90% anywhere else. Another test was also done with regard to clones and I have to admit I wasn’t familiar with this, and can’t repeat it in detail as the other result was just sinking in, but apparently there weren’t enough cells to do this which was good. He said if they had run the test on a new patient and got these results there would be no reason to consider redoing them.

Like last time I asked B if he was glad he asked and this time he was. I suppose it was like an early birthday present for him.

Woo foo

A few appointments ago when we had a woo hoo and a couple of WTFs Roo commented it was more of woo foo, so let’s see how today’s appointment went on the woo hoo/foo-omitor.  Oh, and Chris accompanied me whilst B slept it up at home.

Hug each off one of the health care assistants – woo hoo

Prof said I was very intelligent – WOO HOO (Chris restrained herself from commenting that I was a real smart arse)

Prof said he was perplexed – hint of foo

Paraprotein in blood not detectable – woo hoo

Cytogenetic results not in – mmm as I shoulder shrug – as in not that important in the scheme of things…

Plasma cell level from bone marrow sample – 90% foo foo foo foo foo foo foo

Prof showed me the computer screen to show he wasn’t getting confused at his age after we had a déjà vu moment of conversation from our last appointment but in reversed roles…

Prof: ‘It’s 90%.’

Me:  ’90!’

Prof: ’90.’

Me: ‘Hahahahahahahahahahahahahaha!’ Okay, well obviously not that bit, the Prof didn’t laugh last time.

Chris said later that she thought I was possibly the only myeloma patient he saw who laughed at such news but as I’ve said before being miserable doesn’t cure myeloma – correct me if I’m wrong.

So my monoclonal protein level as at 29 July is not detectable yet the plasma cell content of my bone marrow as at 5 July is 90%.  As I explained to B the sample could theoretically have hit a pocket of plasma cells and the rest of my marrow could be as clean as a whistle but that still left a pocket of not 10%, not 20% but 90%!

Prof said that somehow there was a 90% content sitting there inactive – as shown by the still undetectable paraprotein level.

I asked if it was likely that if a bone marrow sample had been taken after my transplant it would have shown the same result and he said yes.

 So where do we go from here?  Another stem cell transplant using my own cells (autologus/autograft) followed by a mini one using donor cells (allogenic/allograft) was recommended.  We’ll discuss this at our next appointment which will be with the transplant doctor.

And a definite woo hoo was getting on the scales and being 2kg (4 lbs) lighter than six weeks ago – it looks like that extra walking is paying off.  Although after my sugar binge yesterday – 500ml of Dr Pepper and almost* the whole of a 200g bag of chewy sweets that might change.

* I forced some (one or two) on B and Bud so I couldn’t be accused of consuming the whole bag but even so B was heard to say ‘Have you eaten ALL those?’ – mind you I think he might have been talking to Bud.